January 2026

Discovery of VU6052254: A Novel, Potent M1 Positive Allosteric Modulator

Julie L. Engers, Joseph D. Bungard, Christopher C. Presley, Irene Zagol-Ikapitte, Katherine J. Watson, Sichen Chang, Colin O’Carroll, P. Markus Dey, Ethan S. Burstein, Jonathan W. Dickerson, Analisa Thompson Gray, Michael Bubser, Jerri M. Rook, Hyekyung P. Cho, Valerie M. Kramlinger, Olivier Boutaud, Carrie K. Jones, P. Jeffrey Conn, Darren W. Engers, Craig W. Lindsley*

Recent Advances in Long-Acting Antiviral Agents: Innovations in Design and Strategies for Extended Duration.

Wang S, Ma F, Lindsley CW, Xu S, Liu X, Zhan P.

 

Phenotypic Screening: A Cornerstone Engine for Discovering Original Anti-Infective Drugs.

Xu S, Wang M, Shi D, Lindsley CW, Kim M, Sun Y, Zhan P.

Structural Biology Enabling Drug Discovery

Natural Products Driven Medicinal Chemistry

What Is Pink Cocaine? The Dark Reality behind a Colorful Name

Chronic Traumatic Encephalopathy (CTE): A Brief Historical Overview and Recent Focus on NFL Players

Discovery of VU6052254: A Novel, Potent M1 Positive Allosteric Modulator

Discovery of VU0467319: an M1 Positive Allosteric Modulator Candidate That Advanced into Clinical Trials

Classics in Chemical Neuroscience: Tianeptine

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