Vanderbilt University | School of Medicine – Basic Science

“The Reading List” in dark teal with a drawing, in gold tones, of a person with long hair, sitting cross legged and reading a book.

First or corresponding authors are identified with an asterisk. Faculty with appointments in Basic Sciences are listed in red. Only Vanderbilt collaborators are listed except for first authors.

Week of April 22

By Basic Sciences department

Biochemistry

Human gene regulatory evolution is driven by the divergence of regulatory element function in both cis and trans. Cell Genomics.
Tyler Hansen*, Sarah Fong*, Jessica Day, John Capra, Emily Hodges.

“We used our ATAC-STARR-seq method to investigate and characterize cis and trans gene regulatory activity differences between human and rhesus LCLs,” Tyler Hansen.

Highlighted on the Basic Sciences website.
In Vivo and In Vitro Induction of Cytochrome P450 3A4 by Thalidomide in Humanized-Liver Mice and Experimental Human Hepatocyte HepaSH cells. Chemical Research in Toxicology.
Shotaro Uehara* (Central Institute for Experimental Medicine and Life Science), F Peter Guengerich.

Cell and Developmental Biology

Generation and characterization of temperature-sensitive alleles encoding GPI anchored proteins Psu1 and Dfg502 in Schizosaccharomyces pombe. microPublication Biology.
Bita Tavafoghi*, Liping Ren, Kathleen Gould, Alaina Willet.

Molecular Physiology and Biophysics

Immunoproteasomal Processing of IsoLG-Adducted Proteins Is Essential for Hypertension. Circulation Research.
Néstor de la Visitación*, Wei Chen, Jaya Krishnan, Justin Van Beusecum, Venkataraman Amarnath, Elizabeth Hennen, Shilin Zhao, Mohammad Saleem, Mingfang Ao, Sergey Dikalov, Anna Dikalova, David Harrison, David Patrick.
Long COVID-19 and Peripheral Serotonin: A Commentary and Reconsideration. Journal of Inflammation Research.
George Anderson* (Yale University School of Medicine), James Sutcliffe.

Pharmacology

The fasciola cinereum of the hippocampal tail as an interventional target in epilepsy. Nature Medicine.
Ryan Jamiolkowski* (Stanford University), Quynh-Anh Nguyen*.

Highlighted on the Basic Sciences website.
CryoEM structures reveal how the bacterial flagellum rotates and switches direction. Nature Microbiology.
Prashant Singh*, Pankaj Sharma, Margo Goldfarb, Tina Iverson.

“My grandfather built motors that powered big machines. In a lab not so different from his workshop, my colleagues and I uncovered the assembly of the bacterial motor,” Prash Singh.

Highlighted on the Basic Sciences website.
Morphological and electrophysiological characterization of a novel displaced astrocyte in the mouse retina. Glia.
Joseph Holden*, Lauren Wareham, David Calkins*.
Brain-derived neurotrophic factor scales presynaptic calcium transients to modulate excitatory neurotransmission. PNAS.
Camille Wang*, Clara McCarthy, Natalie Guzikowski, Ege Kavalali, Lisa Monteggia*.
Discovery of Protease-Activated Receptor 4 (PAR4)-Tethered Ligand Antagonists Using Ultralarge Virtual Screening. ACS Pharmacology & Translational Science.
Shannon Smith*, Jackson Cassada, Lukas Von Bredow, Kevin Erreger, Emma Webb, Trevor Trombley, Jacob Kalbfleisch, Irene Zagol-Ikapitte, Valerie Kramlinger, Jacob Bouchard, Sidnee Mitchell, Craig Lindsley, Jens Meiler*, Heidi Hamm*.
Therapeutic Potential for Metabotropic Glutamate Receptor 7 Modulators in Cognitive Disorders. Molecular Pharmacology.
Harrison Parent, Colleen Niswender.
The Michael addition of thiols to 13-oxo-octadecadienoate (13-oxo-ODE) with implications for LC-MS analysis of glutathione conjugation. Journal of Biological Chemistry.
William Boeglin, Donald Stec, Saori Noguchi, Wade Calcutt, Alan Brash.

From our research cores

Creative Data Solutions

DIFFERENTIAL SIGNALING EFFECTS OF ESCHERICHIA COLI AND STAPHYLOCOCCUS AUREUS IN HUMAN WHOLE BLOOD INDICATE DISTINCT REGULATION OF THE NRF2 PATHWAY. Shock.
Allison Pourquoi*, Michael Miller, Stephen Koch, Katharine Boyle, Victoria Surratt, Hong Nguyen, Sourav Panja, Jean-Philippe Cartailler, Shristi Shrestha, Ryan Stark*.

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Vanderbilt University School of Medicine Basic Sciences
MRB III U-B1200 465 21st Avenue South
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Phone: (615) 322-0907 | basicsciences@vanderbilt.edu

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