Recently published

• Learning cell identity in immunology, neuroscience, and cancer. Seminars in Immunopathology.
  Stephanie Medina, Rebecca Ihrie, Jonathan Irish.
  
  
• The transcriptional response to acute cocaine is inverted in male mice with a history of cocaine self-administration and withdrawal throughout the mesocorticolimbic system. Molecular and Cellular Neuroscience.
  Soren Emerson, Maxime Chevée, Erin Calipari.
  
  
• Animal Model Reveals Mechanism of Hippocampal Hyperactivity in Psychosis. Schizophrenia Bulletin.
  Stephan Heckers, Christine Konradi.
  
  
• FEMA GRAS assessment of natural flavor complexes: Lemongrass oil, chamomile oils, citronella oil and related flavoring ingredients. Food and Chemical Toxicology.
  Thomas Rosol (Ohio University), F. Peter Guengerich.
  
  
• Structural analysis of the P132L disease mutation in caveolin-1 reveals its role in assembly of oligomeric complexes. Journal of Biological Chemistry.
  Bing Han (University of Virginia), Alican Gulsevin, Angie Deng, Hassane Mchaoraub, Erkan Karakas, Jens Meiler.
  
  
• Systemic kappa opioid receptor antagonism accelerates reinforcement learning via augmentation of novelty processing in male mice. Neuropsychopharmacology.
  Zahra Farahbakhsh, Keaton Song, Hannah Branthwaite, Kirsty Erickson, Snigdha Mukerjee, Suzanne Nolan, Cody Siciliano.
  
  “We tested if widely accepted theories of kappa opioid receptor (KOR) function help us to predict how pharmacologically targeting this receptor affects behavior. Turns out not so much...” Cody Siciliano.
  
  
• Human and bacterial TatD enzymes exhibit apurinic/apyrimidinic (AP) endonuclease activity. Nucleic Acids Research.
  Jonathan Dorival, Brandt Eichman.
  
  
• BioID2 screening identifies KIAA1671 as an EPS8 proximal factor that marks sites of microvillus growth. Molecular Biology of the Cell.
  Isabella Gaeta, Matthew Tyska.
  
  “We used biotin proximity labeling to probe for new molecules involved in microvilli biogenesis,” Isabella Gaeta.
  
  
• Chemistry, structure and function of approved oligonucleotide therapeutics. Nucleic Acids Research.
  Martin Egli.
  
  
• Harnessing prostaglandin E2 signaling to ameliorate autoimmunity. Trends in Immunology.
  Juliann Burkett, Amanda Doran, Maureen Gannon.
  
  “A recent paper co-authored by [the Amanda Doran lab] proposes that PGE2 plays both proinflammatory and pro-resolutory roles in the etiology of autoimmunity, and harnessing this signaling pathway might help prevent autoimmune attack,” VUMC Molecular Pathogenesis.
  
  
• Using mass spectrometry imaging to visualize age-related subcellular disruption. Frontiers in Molecular Biosciences.
  Kelly Hogan (Pennsylvania State University), Heather Beasley, Antentor Hinton Jr.
  
  
• Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization. Circulation.
  Kevin Bersell, Tao Yang, Jonathan Mosley, Andrew Glazer, Andrew Hale, Dmytro Kryshtal, Kyungsoo Kim, Jonathan Brown, Joe-Elie Salem, Courtney Campbell, Quinn Wells, Amanda Johnson, Laura Short, Marcia Blair, Christian Shaffer, Shan Parikh, Quanhu Sheng, Prince Kannankeril, John York, Thomas Wang, Bjorn Knollmann, Dan Roden.
  
  
• Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin. iScience.
  Susan Qualls-Histed, Casey Nielsen, Jason MacGurn.
  
  
• Editorial: Signaling mechanisms of synapse assembly. Frontiers in Synaptic Neuroscience.
  Zhihui Liu (Stanford University), Richard Sando
  

Preprints

• Sensitivity to outcome devaluation in operant tasks is better predicted by food restriction level than reinforcement training schedule in mice. bioRxiv.
  Maxime Chevée, Courtney Kim, Nevin Crow, Emma Follman, Erin Calipari.

Highlighted across the web

• Photoperiod Impacts Nucleus Accumbens Dopamine Dynamics. eNeuro.
  Alexis Jameson, Justin Siemann, James Melchior, Erin Calipari, Douglas McMahon, Brad Grueter.
  Highlighted in the VUMC Reporter.

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