Recently published

• Human IgE mAbs identify major antigens of parasitic worm infection. Journal of Allergy and Clinical Immunology.
  Azadeh Hadadianpour, Jacob Daniel, Jian Zhang, Benjamin Spiller, Stokes Peebles Jr., Scott Smith.
  
  
• Tissue registration and exploration user interfaces in support of a human reference atlas. Communications Biology. 
  Katy Börner (Indiana University), Jeffrey Spraggins, Heath Patterson.
  
  
• From bench to bedside: Improving the clinical safety of GalNAc–siRNA conjugates using seed-pairing destabilization. Nucleic Acids Research.
  Mark Schlegel (Alnylam Pharmaceuticals, Inc.), Martin Egli.
  
  
• Merging of ventral fibers at adhesions drives the remodeling of cellular contractile systems in fibroblasts. Cytoskeleton.
  Shwetha Narasimhan, William Holmes, Irina Kaverina.
  
  
• Unbiased Quantification of Golgi Scattering and Golgi-Centrosome Association. Golgi.
  Keyada Frye, Xiaodong Zhu, Irina Kaverina.
  
  
• Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization. Circulation.
  Kevin Bersell, Tao Yang, Jonathan Mosley, Andrew Glazer, Andrew Hale, Dmytro Kryshtal, Kyungsoo Kim, Jonathan Brown, Joe-Elie Salem, Courtney Campbell, Quinn Wells, Amanda Johnson, Laura Short, Marcia Blair, Christian Shaffer, Shan Parikh, Quanhu Sheng, Prince Kannankeril, John York, Thomas Wang, Bjorn Knollmann, Dan Roden.
  
  
• GluN2D expression is regulated by restraint stress and supports active stress coping bouts. Neuropharmacology.
  Marie Doyle, Jordan Brown, Danny Winder.
  
  
• Persistent challenges in the development of an mGlu7 PAM in vivo tool compound: The discovery of VU6046980. Bioorganic & Medicinal Chemistry Letters.
  Jacob Kalbfleisch, Alice Rodriguez, Xia Lei, Kelly Weiss, Annie Blobaum, Olivier Boutaud, Colleen Niswender, Craig Lindsley.
  
  
• Formation of extramembrane β-strands controls dimerization of transmembrane helices in amyloid precursor protein C99. Proceedings of the National Academy of Sciences.
  George Pantelopulos (Boston University), Daisuke Matsuoka, James Hutchison, Charles Sanders.
  
  
• BCL-xL inhibition potentiates cancer therapies by redirecting the outcome of p53 activation from senescence to apoptosis. Cell Reports.
  Vijaya Bharti (The Ohio State University), Rebecca Shattuck-Brandt, Ann Richmond, Vivian Weiss.
  
  
• Ned Seeman and the prediction of amino acid-basepair motifs mediating protein-nucleic acid recognition. Biophysical Journal.
  Martin Egli.
  
  
• Imaging Cataract-Specific Peptides in Human Lenses. Cells.
  Kevin Schey, Zhen Wang, Kristie Rose, David Anderson.
  
  
• Task parameters influence operant response variability in mice. Psychopharmacology. 
  Emma Follman, Maxime Chevée, Courtney Kim, Amy Johnson, Jennifer Tat, Michael Leonard, Erin Calipari.
  
  
• MALDI TIMS IMS of Disialoganglioside Isomers─GD1a and GD1b in Murine Brain Tissue. Analytical Chemistry.
  Katerina Djambazova, Martin Dufresne, Angela Kruse, Richard Caprioli, Jeffrey Spraggins.
  
  
• Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models. Proceedings of the National Academy of Sciences.
  Kevin Teuscher, Somenath Chowdhury, Kenneth Meyers, Jianhua Tian, Jiqing Sai, Mayme Van Meveren, Taylor South, John Sensintaffar, Tyson Rietz, Soumita Goswami, Jing Wang, Brian Grieb, Shelly Lorey, Gregory Howard, Qi Liu, William Tansey, Taekyu Lee, Stephen Fesik.
  
  
• How T118M peripheral myelin protein 22 predisposes humans to Charcot-Marie-Tooth disease. Journal of Biological Chemistry.
  Katherine Stefanski, Geoffrey Li, Justin Marinko, Bruce Carter, David Samuels, Charles Sanders. 
  
  
• Replication fork uncoupling causes nascent strand degradation and fork reversal. Nature Structural & Molecular Biology.
  Tamar Kavlashvili, Wenpeng Liu, Taha Mohamed, David Cortez, James Dewar.
  
  
• CLASP2 facilitates dynamic actin filament organization along the microtubule lattice. Molecular Biology of the Cell.
  Nicole Rodgers, Elizabeth Lawrence, Avishkar Sawant, Nadia Efimova, Gabriela Gonzalez-Vasquez, Tara Hickman, Irina Kaverina, Marija Zanic.
  
  
• Feedback in the β-catenin destruction complex imparts bistability and cellular memory. Proceedings of the National Academy of Sciences.
  Mary Jo Cantoria (University of Arizona), Ethan Lee.
  
  
• Wnt Signaling in the Phenotype and Function of Tumor-Associated Macrophages. Cancer Research.
  Megan Tigue, Matthew Loberg, Jeremy Goettel, Ethan Lee, Vivian Weiss.
  
  
• Sex Hormones in Breast Cancer Immunity. Cancer Research.
  Ebony Hargrove-Wiley, Barbara Fingleton.
  

Pre-prints

• LIQ HD (Lick Instance Quantifier Home cage Device): An open-source tool for recording undisturbed two-bottle drinking behavior in a home cage environment. bioRxiv.
  Nicholas Petersen, Danielle Adank, Ritika Raghavan, Danny Winder, Marie Doyle.

Highlighted across the web

• Dopamine signaling in the nucleus accumbens core mediates latent inhibition. Nature Neuroscience.
  Munir Kutlu, Jennifer Zachry, Patrick Melugin, Jennifer Tat, Stephanie Cajigas, Atagun Isiktas, Dev Patel, Cody Siciliano, Erin Calipari.
  Highlighted on the Vanderbilt Research News website.
  
  
• Ubiquitination drives COPI priming and Golgi SNARE localization. Cell Biology.
  Swapneeta Date, Peng Xu, Nathaniel Hepowit, Nicholas Diab, Jordan Best, Boyang Xie, Jiale Du, Eric Strieter, Lauren Jackson, Jason MacGurn, Todd Graham.
  Featured on the Vanderbilt Research News website.
  
  
• Proteome Remodeling of the Eye Lens at 50 Years Identified With Data-Independent Acquisition. Molecular & Cellular Proteomics.
  Lee Cantrell, Romell Gletten, Kevin Schey.
  Featured on the Vanderbilt Research News website.
  

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