Recently published

• What does Juneteenth mean in STEMM? Cell.
  Heather Beasley, Alexandra Clark (The University of Texas at Austin), Aleena Garner (Harvard University), Frankie Heyward (Harvard Medical School), Erika Moore (University of Maryland), Robin Nelson (Arizona State University), Keisha Ray (University of Texas Health Science Center at Houston), Sophielle Silvers (Pennsylvania State University), Dominique Stephens, Yvon Woappi (Columbia University).
  
  
• Stories from Hmong in STEMM. Trends in Genetics.
  Zer Vue, Moua Yang (Harvard Medical School), Shany Yang (University of Michigan), Pajau Vangay (Hypothesis Fund), Tou Yia Vue (University of New Mexico Health Sciences Center), Kieng Bao Vang (CCS Associates, Inc.), Kao Lee Yang (University of Wisconsin-Madison, Madison).
  
  
• Awakening: Losing then finding myself in STEMM. Cell.
  Elsie Calderón-Spencer.
  
  
• An immunosuppressed microenvironment distinguishes lateral ventricle-contacting glioblastomas. JCI Insight.
  Todd Bartkowiak, Sierra Lima, Madeline Hayes, Akshitkumar Mistry, Asa Brockman, Justine Sinnaeve, Nalin Leelatian, Caroline Roe, Bret Mobley, Silky Chotai, Kyle Weaver, Reid Thompson, Lola Chambless, Rebecca Ihrie, Jonathan Irish.
  
  “Recent work co-authored by [Jonathan Irish] shows results that characterize immunotherapeutically targetable features of macrophages and suppressed lymphocytes in [glioblastomas] defined by MRI-detectable lateral ventricle contact,” VUMC Molecular Pathogenesis.
  
  
• Repair and tolerance of DNA damage at the replication fork: A structural perspective. Current Opinion in Structural Biology.
  Brandt Eichman.
  
  
• Development of a Kinetic ELISA and Reactive B Cell Frequency Assay to Detect Respiratory Syncytial Virus Pre-Fusion F Protein-Specific Immune Responses in Infants. Journal of the Pediatric Infectious Diseases Society.
  Stephanie Rolsma, Sandra Yoder, Rachel Nargi, Eric Brady, Natalia Jimenez-Truque, Isaac Thomsen, Robert Carnahan, Rachel Sutton, Erica Armstrong, James CroweJr., Kathryn Edwards, Buddy Creech.
  
  “Work co-authored by [James Crowe] found that kELISA targeting [RSV] pre-F epitopes and an RBF assay targeting RSV F-specific B cells generally allow discrimination between maternally and infant-derived [antibodies],” VUMC Molecular Pathogenesis.
  
  
• Mechanistic basis for potent neutralization of Sin Nombre hantavirus by a human monoclonal antibody. Nature Microbiology.
  Robert Stass (University of Oxford), Taylor Engdahl, Nathaniel Chapman, Rachael Wolters, Laura Handal, Summer Diaz, James Crowe Jr.
  
  “We demonstrate the structural basis of Sin Nombre neutralization by a near germline human antibody, SNV-42,” Taylor Engdahl.
  
  
• Immune profiling of murine cardiac leukocytes identifies Trem2 as a novel mediator of hypertensive heart failure. Cardiovascular Research.
  Duncan Smart, Daniel Fehrenbach, Jean Wassenaar, Vineet Agrawal, Niki Fortune, Debra Dixon, Matthew Cottam, Alyssa Hasty, Anna Hemnes, Amanda Doran, Deepak Gupta, Meena Madhur.
  
  
• Insulin secretion hot spots in pancreatic β cells as secreting adhesions. Frontiers in Cell and Developmental Biology.
  Margret Fye, Irina Kaverina.
  
  
• Tissue Mass Spectrometry: How Solid Is Our Future? Clinical Chemistry.
  Daisy Unsihuay (University of Pennsylvania), Jeffrey Spraggins.
  
  
• Alkylation of NH-sulfoximines under Mitsunobu-type conditions. Organic and Biomolecular Chemistry.
  Cayden Dodd, Daniel Schultz, Jinming Li, Craig Lindsley, Aaron Bender.
  
  
• Microscopy-Directed Imaging Mass Spectrometry for Rapid High Spatial Resolution Molecular Imaging of Glomeruli. Journal of the American Society for Mass Spectrometry.
  Allison Esselman, Nathan Patterson, Lukasz Migas, Martin Dufresne, Katerina Djambazova, Madeline Colley, Raf Van de Plas, Jeffrey Spraggins.
  

Highlighted across the web

• The selective RyR2 inhibitor ent-verticilide suppresses atrial fibrillation susceptibility caused by Pitx2 deficiency. Journal of Molecular and Cellular Cardiology.
  Kyungsoo Kim, Daniel Blackwell, Madelaine Thorpe, Jeffrey Johnston, Razvan Cornea, Björn Knollmann.
  
  Highlighted in the VUMC Reporter.
  
  
• CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth. Molecular Cancer.
  Jinming Yang, Kensie Bergdorf, Chi Yan, Weifeng Luo, Sheau-Chiann Chen, Gregory Ayers, Qi Liu, Xiao Liu, Mark Boothby, Vivian Weiss, Sarah Groves, Austin Oleskie, Vito Quaranta, Ann Richmond.
  
  Highlighed on the Basic Sciences website.
  

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